P2: WHEN THE COMMON COLD TURNS DEADLY: ANAPHYLAXIS WITH ANDROGRAPHIS PANICULATA

When a healthy diet turns deadly

The health benefits of a high fiber diet (HFD) result in part from the action of metabolic end products made by gut commensals on the host epithelium. Butyrate is one such beneficial metabolite; however, butyrate paradoxically enhances the capacity of Escherichia coli-produced Shiga toxin type 2 (Stx2) to kill tissue culture cells. We recently showed that mice fed an HFD exhibited increased but...

Assessment report on Andrographis paniculata Nees, folium

Perspective of Andrographis paniculata in Neurological Disorders

Andrographis paniculata (Burm. F.) Wall. Ex Nees (family Acanthaceae) also known as Kalmegh (Figure 1), is extremely bitter in taste and it is often referred to as the “the king of bitters”. This plant has been used as bitter tonic, stimulant, and aperients in Ayurvedic and other traditionally known health care systems widely practiced in India and other Asiatic countries. Amongst numerous plan...

Is Andrographis paniculata extract and andrographolide anaphylactic?

Andrographis paniculata, "King of bitters" is a popularly known medicinal plant extensively used in many parts of the world for treatment of various diseases. Since recent past, anaphylactic/allergic type adverse events were reported upon A. paniculata usage, the study aimed to evaluate the anaphylactic and anaphylactoid potential of A. paniculata extract and andrographolide (a major phytoactiv...

Hepatoprotective Diterpenoids Isolated from Andrographis paniculata

Andrographis paniculata (Burm.f.) Nees (Acanthaceae), a plant widely used as traditional herbal medicine in many countries, has drawn attention of the researchers in recent years. Its major constituents are diterpenoids and flavonoids. This article reviews the anti-hepatotoxic effects of A. paniculata extract and derivative compounds, such as andrographolide, the major active compound, most stu...